News on Immunotherapy

Stay Updated on the Latest Advancements in Immunotherapy

AIM with Immunotherapy reviews the latest medical publications to highlight stories related to treatment with immunotherapy in oncology.

Stay updated in the immunotherapy field with articles cultivated for you and listed by date from most to least recent. To read the articles, hover and click on the individual titles. The titles will link readers to articles on immune-related adverse events, FDA approvals of relevant therapies, health outcomes, and changes impacting clinical management of cancers treated with immunotherapy.

Priority is given to primary-sourced, full-length articles provided by the publishers without charge. Only a select few major, paradigm-changing updates of abstracts are included.



March 25, 2025

Patient-reported outcomes with adjuvant nivolumab versus placebo after complete resection of stage IIB/C melanoma in the randomized phase 3 CheckMate 76K trial


March 19, 2025

FDA Approves Pembrolizumab for HER2 Positive Gastric or Gastroesophageal Junction Adenocarcinoma Expressing PD-L1 (CPS 1)


March 13, 2025

Adjuvant PD-1 Blockade With Camrelizumab for Nasopharyngeal Carcinoma


March 11, 2025

Blocking MIF secretion enhances CAR T-cell efficacy against neuroblastoma


March 7, 2025

Abstract Thinking and Statins With Immune Checkpoint Inhibitors: Enough to Change Clinical Practice?


March 8, 2025

Antibody-Drug Conjugates: The Toxicities and Adverse Effects That Emergency Physicians Must Know


March 3, 2025

Safety and efficacy of immune checkpoint therapy for the treatment of patients with cardiac metastasis: a multicenter international retrospective study


March 1, 2025

A case of immune checkpoint inhibitor-related conjunctivitis controlled by tacrolimus eye drops


March 1, 2025

Hidradenitis suppurativa induced by ipilimumab and nivolumab: A rare association


February 12, 2025

Immune Checkpoint Inhibitors in Field Cancerization and Keratinocyte Cancer Prevention


February 10, 2025

Acquired Generalized Lipodystrophy as an Adverse Event of Combined Immune Checkpoint Inhibitor Therapy


February 6, 2025

Pembrolizumab in Patients With Advanced Clear Cell Gynecological Cancer


February 3, 2025

Safety and Tolerability of Letetresgene Autoleucel (GSK3377794): Pilot Studies in Patients with Advanced Non–Small Cell Lung Cancer


February 3, 2025

Phase I/II Study of the Aurora Kinase A Inhibitor Alisertib and Pembrolizumab in Refractory, Rb-Deficient Head and Neck Squamous Cell Carcinomas


January 9, 2025

Anti-CTLA-4 generates greater memory response than anti-PD-1 via TCF-1


January 7, 2025

Neoadjuvant anti-PD-1 alone or in combination with anti-TIGIT or an oncolytic virus in resectable stage IIIB–D melanoma: a phase 1/2 trial


January 6, 2025

Ocular surface disease related to tisotumab vedotin-tftv


January 4, 2025

Gut microbiome and immune checkpoint inhibitor toxicity


December 30, 2024

Phase II Open-Label Trial of Brentuximab Vedotin with Pembrolizumab in PD-1–Pretreated Metastatic Non–Small Cell Lung Cancer and Metastatic Cutaneous Melanoma


December 27, 2024

FDA approves nivolumab and hyaluronidase-nvhy for subcutaneous injection


December 23, 2024

Immune Checkpoint Inhibitor–Induced Vitiligo-Like Depigmentation


December 18, 2024

Neoadjuvant Pembrolizumab in Stage I-III Deficient Mismatch Repair Colon Cancer: A Clinical Trial


December 16, 2024

TIGIT and PD-L1 co-blockade promotes clonal expansion of multipotent, non-exhausted antitumor T cells by facilitating co-stimulation


December 13, 2024

FDA approves cosibelimab-ipdl for metastatic or locally advanced cutaneous squamous cell carcinoma


December 3, 2024

Compassionate access to virus-specific T cells for adoptive immunotherapy over 15 years


November 27, 2024

Nivolumab in Patients With Advanced or Metastatic Malignancies, Including Rare Cancers: Results of CheckMate 627, an Adaptive Basket Design Clinical Trial


November 27, 2024

Nivolumab plus Ipilimumab in Microsatellite-Instability–High Metastatic Colorectal Cancer


November 21, 2024

Low-Dose Anti-PD(L)1 for the Treatment of Solid Malignancies


November 21, 2024

FDA grants accelerated approval to zanidatamab-hrii for previously treated unresectable or metastatic HER2-positive biliary tract cancer


November 20, 2024

Nemvaleukin alfa, a modified interleukin-2 cytokine, as monotherapy and with pembrolizumab in patients with advanced solid tumors (ARTISTRY-1)


November 10, 2024

Management of Immunotherapy-Related Toxicities, Version 2.2024


November 8, 2024

FDA approves obecabtagene autoleucel for adults with relapsed or refractory B-cell precursor acute lymphoblastic leukemia


November 4, 2024

CAR T Cells and T-Cell Therapies for Cancer


October 30, 2024

Type I MET inhibitors cooperate with PD-1 blockade to promote rejection of hepatocellular carcinoma


October 29, 2024

Immune-mediated colitis after immune checkpoint inhibitor therapy


October 23, 2024

Combined PD-1 and CTLA-4 Blockade in an International Cohort of Patients with Acral Lentiginous Melanoma


October 18, 2024

Genetic Factors Associated with Clinical Response in Melanoma Patients Treated with Talimogene Laherparapvec: A Single-Institution Retrospective Analysis


October 16, 2024

Probiotic neoantigen delivery vectors for precision cancer immunotherapy


October 9, 2024

Phase I/II study of BMS-986156 with ipilimumab or nivolumab with or without stereotactic ablative radiotherapy in patients with advanced solid malignancies


October 5, 2024

Thromboembolism during immune checkpoint inhibitor therapy: frequency and risk factors


October 3, 2024

FDA approves neoadjuvant/adjuvant nivolumab for resectable non-small cell lung cancer


October 2, 2024

MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution


September 20, 2024

Adjuvant Nivolumab for Localized Renal Cell Carcinoma at High Risk of Recurrence After Nephrectomy: Part B of the Randomized, Placebo-Controlled, Phase III CheckMate 914 Trial


September 16, 2024

Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial


September 12, 2024

Five latent factors underlie response to immunotherapy


September 3, 2024

Neoadjuvant immune checkpoint blockade in women with mismatch repair deficient endometrial cancer: a phase I study


August 29, 2024

Clinical and pathological characterization of Tebentafusp-associated skin toxicity – a cohort study with 33 patients


August 29, 2024

Identification of Immune Checkpoint Inhibitor–Induced Diabetes


August 20, 2024

Predominance of hyper-progression in mucosal melanoma during anti-PD-1 monotherapy treatment


August 13, 2024

Single Institution Experience with Immune Checkpoint Inhibitors in Vulvar and Vaginal Melanomas


August 8, 2024

Health and Economic Outcomes of Pembrolizumab in the Treatment of Metastatic Non-small Cell Lung Cancer (mNSCLC) and Melanoma in Italy


August 8, 2024

Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunity


August 7, 2024

Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy: Analysis of Six Clinical Trials


August 6, 2024

Clinical features associated with immune checkpoint inhibitor nephritis: a single-center clinical case series


August 2, 2024

FDA grants accelerated approval to afamitresgene autoleucel for unresectable or metastatic synovial sarcoma


July 23, 2024

Evaluation of safety outcomes between nivolumab regimens with differing dosing patterns


July 17, 2024

Neoadjuvant and adjuvant pembrolizumab in advanced high-grade serous carcinoma: the randomized phase II NeoPembrOV clinical trial


July 16, 2024

Pre-existing autoimmune disease as a risk factor for immune-related adverse events in cancer patients receiving immune checkpoint inhibitors


July 4, 2024

Research progress on the impact of intratumoral microbiota on the immune microenvironment of malignant tumors and its role in immunotherapy


July 3, 2024

RELATIVITY-048: Triplet Immunotherapy Shows Activity in Untreated Advanced Melanoma


June 27, 2024

Impact of opioid analgesics on survival in cancer patients receiving immune checkpoint inhibitors


June 26, 2024

Multiple immune-related adverse events secondary to checkpoint inhibitor therapy in patients with advanced cancer: association with treatment effectiveness


June 19, 2024

Challenges and opportunities in cancer immunotherapy: a Society for Immunotherapy of Cancer (SITC) strategic vision


June 7, 2024

Risk of Second Tumors and T-Cell Lymphoma after CAR T-Cell Therapy


June 6, 2024

Replimune Announces Positive Topline Primary Analysis Data by Independent Central Review from IGNYTE Clinical Trial of RP1 plus Nivolumab in Anti-PD1 Failed Melanoma


June 2, 2024

Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma


May 30, 2024

From decision to reflection: understanding the experiences and unmet care needs of patients treated with immunotherapy for melanoma in the adjuvant or metastatic setting


May 23, 2024

Intensity-Modulated Reirradiation Therapy With Nivolumab in Recurrent or Second Primary Head and Neck Squamous Cell Carcinoma: A Nonrandomized Controlled Trial


May 16, 2024

FDA grants accelerated approval to tarlatamab-dlle for extensive stage small cell lung cancer


May 16, 2024

FDA Grants Accelerated Approval to Lisocabtagene Maraleucel for Relapsed or Refractory Follicular Lymphoma


May 8, 2024

Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy


May 1, 2024

Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)


April 26, 2024

Risk of T-Cell and Second Primary Malignant Neoplasms After CAR T-Cell Therapy


April 23, 2024

Immunologic Profiling of Immune-Related Cutaneous Adverse Events with Checkpoint Inhibitors Reveals Polarized Actionable Pathways


April 22, 2024

Immune checkpoint blockers in solid organ transplant recipients and cancer: the INNOVATED cohort


April 22, 2024

Bispecific Immune Checkpoint Inhibitor Improves Survival in Patients With Gastric Cancer, Regardless of PD-L1 Status


April 17, 2024

Overall Survival with Adjuvant Pembrolizumab in Renal-Cell Carcinoma


April 7, 2024

Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial


April 3, 2024

Immune checkpoint inhibitors for metastatic uveal melanoma: a meta-analysis


March 28, 2024

Safety, efficacy, and biological data of T cell-enabling oncolytic adenovirus TILT-123 in advanced solid cancers from the TUNIMO monotherapy phase I trial


March 18, 2024

Senescence drives immunotherapy resistance by inducing an immunosuppressive tumor microenvironment


March 11, 2024

Neoadjuvant chemo-immunotherapy with camrelizumab plus nab-paclitaxel and cisplatin in resectable locally advanced squamous cell carcinoma of the head and neck: a pilot phase II trial


March 7, 2024

Pembrolizumab Versus Placebo as Adjuvant Therapy in Resected Stage IIB or IIC Melanoma: Final Analysis of Distant Metastasis-Free Survival in the Phase III KEYNOTE-716 Study


March 1, 2024

Prediction of Effectiveness and Toxicities of Immune Checkpoint Inhibitors Using Real-World Patient Data


February 29, 2024

Unveiling cutaneous adverse events and prognosis in immunotherapy for melanoma and squamous cell carcinoma


February 29, 2024

Cancer neoepitopes viewed through negative selection and peripheral tolerance: a new path to cancer vaccines


February 24, 2024

Rheumatic adverse events of immune checkpoint inhibitors in cancer immunotherapy


February 23, 2024

Adjuvant dendritic cell therapy in stage IIIB/C melanoma: the MIND-DC randomized phase III trial


February 21, 2024

FDA Adds Boxed Warning to CAR T-Cell Therapies, but Says Benefits Outweigh Risks of Secondary Cancers


February 19, 2024

Immune-related serious adverse events with immune checkpoint inhibitors: Systematic review and network meta-analysis  


February 16, 2024

FDA Approves First One-time Cell Therapy for a Solid Tumor


February 16, 2024

Neoadjuvant cobimetinib and atezolizumab with or without vemurafenib for high-risk operable Stage III melanoma: the Phase II NeoACTIVATE trial


February 14, 2024

Pan-cancer proteogenomics characterization of tumor immunity


February 8, 2024

Association of Baseline Tumor-Specific Neoantigens and CD8+ T-Cell Infiltration With Immune-Related Adverse Events Secondary to Immune Checkpoint Inhibitors


February 5, 2024

Efficacy and safety of autologous tumor-infiltrating lymphocytes in recurrent or refractory ovarian cancer, colorectal cancer, and pancreatic ductal adenocarcinoma


February 5, 2024

A case of ruptured hepatic metastases during pembrolizumab administration for cutaneous malignant melanoma


January 24, 2024

Immunotherapy eliminates senescent cells, making chemotherapy more efficientL: Study


January 22, 2024

Immunotherapy combination induces ‘robust’ responses in high-risk follicular lymphoma


January 20, 2024

First-Line Nivolumab Plus Ipilimumab Demonstrates Superior PFS in mCRC


January 16, 2024

End-of-Life Immunotherapy Use Increasing in Advanced Melanoma, RCC, NSCLC


January 16, 2024

Colorectal Cancer Patients May Continue to Benefit After Stopping Immunotherapy


January 15, 2024

FDA Approves Pembrolizumab Plus Chemoradiotherapy to Treat FIGO 2014 Stage III-IVA Cervical Cancer


January 13, 2024

Beta-Adrenergic Blockade in Advanced Non-Small Cell Lung Cancer Patients Receiving Immunotherapy: A Multicentric Study


January 11, 2024

Immunotherapy and Radiation Combo Shows Improved Outcomes for Non-small Cell Lung Cancer


January 7, 2024

Atezolizumab May Yield OS Benefit in PD-L1+ Advanced Urothelial Carcinoma


January 6, 2024

Determining Optimal IO Combinations in Advanced NSCLC


January 4, 2024

Anti-CTLA-4 nanobodies offer promising strategy to prevent colitis in cancer immunotherapy


January 3, 2024

Immune cell helps predict skin cancer patients’ chances of responding to treatment