Get the latest news on immunotherapy

July 14, 2021

Regorafenib/nivolumab elicits better responses in patients without liver metastases in mismatch repair-proficient (pMMR)/microsatellite stable (MSS) colorectal cancer (CRC)

July 14, 2021

BEMPEG plus nivolumab achieved “deep and durable” responses in previously untreated metastatic melanoma patients

July 13, 2021

Adjunctive nivolumab reduces risk of death and progression of gastric adenocarcinoma compared to chemotherapy alone

July 12, 2021

FDA approves Keytruda for the treatment of patients with locally advanced cutaneous squamous cell carcinoma

July 12, 2021

Combination of pembrolizumab and low-dose ipilimumab appeared to show significant antitumor activity among patients with advanced melanoma who previously failed immunotherapy

July 11, 2021

Cabozantinib fails to improve progression-free survival and results in more adverse effects in patients with renal cell carcinoma

July 9, 2021

Merk will withdraw Keytruda’s “dangling” indication for gastric cancer

July 8, 2021

Research group led by Herwig Moll identified a potential marker for the success of immunotherapy in lung cancer patients

July 7, 2021

OncoSec, Merck enter agreement for late-stage metastatic melanoma combo

July 7, 2021

Jimmy Hwang, MD, discusses the frontline indications for checkpoint inhibitors in gastric cancer

June 30, 2021

Alpine Immune Sciences to collaborate with Merck on immune-oncology study to evaluate ALPN-202 in combination with Keytruda (pembrolizumab)

June 29, 2021

Merck’s Keytruda-Chemo combo wins European approval in esophagus cancer

June 28, 2021

In surprising flop, Exelixis’ Cabometyx combo with Roche’s Tecentriq fails to extend life in liver cancer

June 28, 2021

Galinpepimut-S plus nivolumab shows promising preliminary benefit in mesothelioma

June 25, 2021

Long-term benefits of nivolumab in pre-treated non-small cell lung cancer

June 24, 2021

Corbus Pharmaceuticals announces topline results from DETERMINE Phase 3 study of lenabasum for treatment of dermatomyositis

June 23, 2021

Rubius Therapeutics announces first patient dosed with RTX-240 in combination with Keytruda in ongoing Phase ½ clinical trial for the treatment of advanced solid tumors

June 23, 2021

Microbiotica’s Live Bacterial Therapeutic, MB097, in development to begin clinical trials in 2022 in immune-oncology

June 22, 2021

MSD’s Keytruda proves effective for non-muscle-invasive bladder cancer

June 22, 2021

Merck says Keytruda extends survival in cervical cancer study

June 22, 2021

Targovax receives Fast Track designation for ONCOS-102 in melanoma

June 21, 2021

‘Suffocating’ cancer: a new headway in melanoma immunotherapy

June 21, 2021

Patients with advanced esophageal squamous cell carcinoma experience improved survival outcomes with addition of nivolumab to ipilimumab or chemotherapy

June 21, 2021

Nivolumab/ipilimumab triplet improves OS in advanced non-small cell lung cancer compared with chemotherapy alone

June 18, 2021

A phase I study of APX005M and cabiralizumab with/without nivolumab in patients with melanoma, kidney cancer or non-small cell lung cancer resistant to anti-PD-(L)1

June 17, 2021

Merck’s KEYNOTE-564 data heralds early adjuvant Keytruda use in renal cancer

June 16, 2021

ODAC panel approves 4 of 6 anti-PD-1/PD-L1 drugs in accelerated approval program

June 15, 2021

Linnaeus Therapeutics announces expanded clinical collaboration with Merck to include multiple additional cohorts to evaluate LNS8801 in combination with Keytruda in patients with advanced cancer

June 14, 2021

Istari Oncology announces FDA granted fast track designation to PVSRIPO for the treatment of advanced melanoma

June 14, 2021

Exelixis announces clinical trial collaboration and supply agreement with Bristol Myers Squibb to evaluate XL092 in combination with immune-oncology therapies in advanced solid tumors

June 11, 2021

Cetuximab after disease progression with immunotherapy in advanced skin cancer

June 10, 2021

Old antidepressants show promise as immuno-oncology treatments in melanoma and colon cancer

June 8, 2021

LARVOL launches platform to curate historical and active immuno-oncology clinical trial data in a digital dashboard

June 8, 2021

APG-115 plus pembrolizumab safe with preliminary efficacy in unresectable or metastatic melanoma or advanced solid tumors

June 7, 2021

Positive preliminary results from Delcath Systems’ FOCUS trial presented at the 2021 ASCO annual meeting

June 7, 2021

Merck & Co announces results at ASCO for Keytruda plus Lenvima for kidney cancer patients

June 7, 2021

An overview of the phase 3 trial assessing nivolumab plus platinum-doublet chemotherapy for resectable non-small cell lung cancer

June 7, 2021

NeoImmune Tech trial data evaluating NT-I7 in combination with pembrolizumab as a treatment for advanced solid tumors presented at ASCO annual meeting

June 7, 2021

Melanoma outcomes are improved with nivolumab alone or with ipilimumab

June 7, 2021

Adjuvant Anti-PD-1 Misses on OS in High-Risk Melanoma

June 7, 2021

Alpine reports 61% ‘clinical benefit’ in early trial of CD28-targeted immune-oncology drug

June 6, 2021

Lifileucel continues to show durable responses in advanced melanoma

June 4, 2021

Surface Oncology to collaborate with Roche on immune-oncology study evaluating SRF388, targeting IL-27, as part of a novel combination in patients with advanced treatment-naïve hepatocellular carcinoma

June 4, 2021

Coherus and Junshi Biosciences announce toripalimab in combination with chemotherapy met primary progression free survival (PFS) endpoint as first line treatment for recurrent or metastatic nasopharyngeal carcinoma (NPC)

June 4, 2021

Alkermes results presented at ASCO 2021 show a dwindling response rate in melanoma patients receiving nemva monotherapy

June 4, 2021

Nanobiotix’s radiotherapy enhancer for tumors also primes the immune system

June 4, 2021

Immunocore presents clinical data further characterizing the overall survival benefit of tebentafusp in metastatic uveal melanoma at the 2021 American Society of Clinical Oncology (ASCO) Annual Meeting

June 4, 2021

Results presented at Asco show a dwindling response rate in melanoma patients receiving Alkermes’ nemvaleukin monotherapy

June 4, 2021

Iovance Biotherapeutics announces clinical data for lifileucel in combination with pembrolizumab in advanced melanoma at ASCO 2021 annual meeting

June 3, 2021

Opdivo, Yervoy combination approved to treat malignant pleural mesothelioma

June 2, 2021

Researchers have identified a protein that helps tumors evade the immune system and, in certain types of cancers, is linked to poorer chance of survival

May 28, 2021

Combination therapy with nivolumab and relatimab prolongs progression-free survival in advanced melanoma

May 25, 2021

Xilio and Merck partner on anti-CTLA-4 antibody in combination with Keytruda in solid tumors

May 24, 2021

Scopus BioPharma Inc. announced the approval of an investigational new drug application by the FDA for CPG-STAT3siRNA, an immune-oncology RNA therapy for the treatment of multiple cancers

May 21, 2021

Japan’s Astellas Pharma and US biotech Seagen have announced updated results from clinical trials evaluating Padcev in combination with Keytruda in patients with locally advanced or metastatic urothelial cancer who are not able to receive cisplatin chemotherapy

May 21, 2021

Trial data shows durable, long-term survival with nivolumab, ipilimumab in patients with non-small cell lung cancer with PD-L1 expression

May 21, 2021

Bristol Myers wins positive opinion in Europe for Opdivo and Yervoy combo for colorectal cancer

May 21, 2021

Boehringer Ingelheim and OSE Immunotherapeutics unveiled preliminary data from a phase 1 trial of BI 7765063 at the 2021 ASCO annual meeting

May 21, 2021

Study shows cancer vaccine may boost immunotherapy effectiveness

May 21, 2021

RYBREVANT is the first fully-human, bispecific antibody approved in lung cancer

May 20, 2021

Researchers reported that targeted metabolic inhibitor stabilizes solid tumors in 60% of patients in phase 1 trial

May 20, 2021

Agenus presents new data on balstilimab and AGEN2373 in ASCO abstracts

May 20, 2021

Adjuvant Opdivo now approved by the FDA as a treatment for esophageal and gastroesophageal junction (GEJ) cancers

May 19, 2021

Merck details Keytruda and Herceptin combination win for stomach cancer at the annual ASCO meeting in 2021

May 19, 2021

New Bristol Myers immunotherapy combo better than Opdivo alone in melanoma study

May 19, 2021

Dual immunotherapy regimen targeting novel lymphocyte-activation gene 3 (LAG-3) immune checkpoint led to a significant progression-free survival (PFS) benefit in patients with advanced melanoma

May 19, 2021

Ascentage Pharma to announce updated results demonstrating clinical potential of alrizomadlin plus pembrolizumab in patients with advanced solid tumors that had failed immunotherapies at ASCO 2021

May 19, 2021

Biomarker panels evaluated by multiplex immunoassays with high analytical performance demonstrated potential complementary values in detection of uveal melanoma

May 19, 2021

6 ½ year outcomes for Opdivo in combination with Yervoy continue to demonstrate durable long-term survival benefits in patients with advanced melanoma

May 19, 2021

Nivolumab plus brentuximab vedotin shows efficacy for patients with mediastinal gray zone lymphoma

May 19, 2021

Merck’s LAG-3-targeting antibody, favezelimab, boosts Keytruda in metastatic colorectal cancer

May 17, 2021

BioMed X Institute and Merck extend collaboration to continue novel research in oncology and autoimmunity

May 14, 2021

Results from phase 3 KEYNOTE-522 trial showed that Keytruda met the dual-primary endpoint of event-free survival for treatment of high-risk early-stage triple-negative breast cancer patients

May 12, 2021

Exelixis’ Cabometyx scores backing from Ipsen in thyroid cancer with full data release set for ASCO

May 12, 2021

Bristol-Myers Squibb will present new data examining the combination of Opdivo plus Yervoy in various cancers in June’s American Society of Clinical Oncology (ASCO) Meeting

May 11, 2021

FDA approval summary of nivolumab plus ipilimumab for the treatments of patients with hepatocellular carcinoma previously treated with sorafenib

May 11, 2021

BostonGene and University of Pennsylvania’s Abramson Cancer Center to collaborate on immunotherapy studies

May 10, 2021

IMV Inc. announced that its lead compound, maveropepimut-S will be investigated in patients with hormone receptor positive/HER2-negative breast cancer

May 10, 2021

Immune-inflammatory biomarkers as prognostic factors for immunotherapy in pretreated advanced urinary tract cancer patients

May 7, 2021

Opdivo sBLA receives FDA acceptance and Priority Review for adjuvant treatment for patients with muscle-invasive urothelial carcinoma

May 7, 2021

New immunotherapy combinations are being explored in small cell lung cancer

May 6, 2021

Microneedles for cancer immunotherapy may lead to minimal invasiveness and side effects

May 6, 2021

Merck’s Keytruda has won FDA clearance to treat new patients with HER2-positive gastric or gastroesophageal junction (GEJ) adenocarcinoma

May 6, 2021

Fusion Pharmaceuticals announces clinical collaboration with Merck to evaluate Fusion’s Targeted Alpha Therapy (TAT) in combination with Merck’s Keytruda in patients with solid tumors expressing IGF-1R

May 5, 2021

Alchemab to collaborate with AstraZeneca to use Alchemab’s Drug Discovery Platform for prostate cancer study

May 5, 2021

Checkmate Pharmaceuticals announces initiation of patient dosing in potential registration trial of Vidutolimod in patients with anti-PD-1 refractory advanced melanoma

May 5, 2021

Replimune provides a regulatory update for its registration-directed clinical trials evaluating RP! In combination with Libtayo

April 30, 2021

FDA panel denies support for maintaining Bristol’s Opdivo as liver cancer treatment

April 29, 2021

ODAC votes to keep Keytruda and Tecentriq accelerated approvals in bladder cancer

April 28, 2021

Biopharmaceuticals announces acceptance of PV-10 immunotherapy abstracts at the American Society of Clinical Oncology (ASCO) 2021 Annual Meeting

April 28, 2021

Jemperli and Zynlonta have been approved by the FDA for advanced endometrial cancer and relapsed large B-cell lymphoma respectively

April 28, 2021

The virtual 2021 Great Debates and Updates in Women’s Oncology meeting presented a lively debate regarding immunotherapy for early triple-negative breast cancer (TNBC)

April 27, 2021

Alkermes initiates ARTISTRY-6 trial of nemvaleukin alfa monotherapy in patients with melanoma

April 26, 2021

Researchers have identified the genetic abnormalities that drive pre-cancer cells into becoming an invasive type of head and neck cancer and patients who are least likely to respond to immunotherapy

April 26, 2021

The FDA’s Oncologic Drugs Advisory Committee will be moving forward with a public review of 6 indications for immune checkpoint inhibitors granted under the agency’s accelerated approval process that later failed to reach thresholds for statistical significance in confirmatory clinical trials

April 23, 2021

ADC Therapeutics nabs its first approval as FDA offers a quick OK for its diffuse large B-cell lymphoma cancer treatment

April 23, 2021

GlaxoSmithKline immunotherapy Jemperli wins FDA approval for recurrent or advanced endometrial cancers with a specific type of genetic error that disrupts cells’ ability to repair DNA

April 23, 2021

Effects of Keytruda sustained after 3.5 years in high-risk stage 3 cutaneous melanoma

April 23, 2021

EU Panel recommends nivolumab/ipilimumab in frontline unresectable malignant pleural mesothelioma

April 22, 2021

Candel Therapeutics has announced it has completed enrollment for its phase I clinical trial in patients with newly diagnosed high-grade glioma to evaluate the safety and efficacy of CAN-2409 in combination with Opdivo

April 22, 2021

Adjuvant nivolumab improved disease-free survival in esophageal and gastroesophageal junction cancers with residual pathologic disease after resection

April 22, 2021

Immunotherapy combinations may hold promise in treatment of late-stage or recurrent endometrial cancer

April 22, 2021

Toripalimab plus chemotherapy as first-line treatment for advanced esophageal cancer reached primary endpoints in phase III clinical study

April 21, 2021

Opdivo has been granted an extended indication for the initial treatment of patients with advanced or metastatic gastric cancer, gastroesophageal junction cancer, and esophageal adenocarcinoma

April 21, 2021

Istari Oncology announces publication of “A phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma” in the BMJ’s Journal for ImmunoTherapy of Cancer

April 16, 2021

IDEAYA reports clinical data from the ongoing phase 1/2 trial evaluating darovasertib monotherapy and binimetnib combination therapy in patients with solid tumors, including metastatic uveal melanoma and skin melanoma

April 15, 2021

AACR Forum Microbiome Pandemonium: Checkpoints and the Microbiome discusses growing evidence for the relationship between gut microbiota and the response of immune checkpoint inhibitors

April 14, 2021

The National Comprehensive Cancer Network (NCCN) Oncology Research Program (ORP) announced that three projects have been selected to study oral decitabine and cedazuridine

April 14, 2021

A new phase I study at the Memorial Sloan Kettering Cancer Center plans to assess the safety of RO7293583 immunotherapy in patients with metastatic melanoma that contains a protein called TYRP1

April 14, 2021

Panel discusses how combination therapies could create better, longer-lasting outcomes

April 13, 2021

The AACR’s Presidential Address, Fighting Melanoma with the Immune System, discussed how researchers are working to change the treatment paradigm for patients with melanoma through next-generation techniques that stimulate immune response and amplify antitumor activity

April 12, 2021

Forum considers when the right time is to utilize CAR-T therapies

April 11, 2021

First Clinical Trials Plenary features practice-changing data from phase III trials

April 10, 2021

Results from the AACR annual meeting show that patients with early-stage non-small cell lung cancer who took a combination of Opdivo and chemotherapy before surgery were nearly 14 times more likely to show no signs of cancer cells in their resected tissue compared with those who got chemo alone

April 10, 2021

Nivolumab plus paclitaxel shows clinical activity in advanced gastric cancer subgroup

April 10, 2021

Unselected autologous tumor infiltrating lymphocyte therapy shows early promise in patients with metastatic melanoma

April 10, 2021

Immunotherapy response prediction using tumor mutational burden may differ between men and women with melanoma

April 10, 2021

A liquid biopsy test to assess plasma cell-free DNA integrity could improve the accuracy of magnetic resonance imaging for predicting the achievement of complete response among patients with locally advanced breast cancer who had received neoadjuvant chemotherapy, according to results presented during Week 1 of the virtual AACR Annual Meeting 2021

April 10, 2021

Copanlisib-rituximab combination cuts lymphoma progression or death by nearly half in CHRONOS-3 trial

April 10, 2021

Neoadjuvant nivolumab plus chemotherapy increased pathological complete response rate in CheckMate-816 lung cancer trial

April 9, 2021

Case report describes myositis flare after initiation of nivolumab for metastatic melanoma in a patient who had previously achieved remission of dermatomyositis

April 9, 2021

The National Institute for Health and Care Excellence (NICE) has issued a preliminary no for NHS use of Bristol-Myers Squibb’s Opdivo/Yervoy combination for treating metastatic non-small-cell lung cancer

April 8, 2021

Merck announced that Keytruda has succeeded in a phase 3 trial in early kidney cancer

April 8, 2021

University of Texas MD Anderson Cancer Center and TriSalus Life Sciences announce collaboration on studies evaluating the administration of investigational SD-101 intravascularly via the FDA cleared Pressure-Enabled Drug Delivery (PEDD) technology across a range of liver and pancreatic solid tumors

April 8, 2021

Merck’s Keytruda demonstrated superior disease-free survival compared with placebo as adjuvant therapy in patients with renal cell carcinoma following surgery

April 7, 2021

PsiOxus Therapeutics updates agreement with Bristol Myers Squibb to advance their clinical stage immune-oncology collaboration to investigate the combination of NG-641 with Opdivo in several tumor types

April 1, 2021

Phase II, multicenter, open-label study in patients with stage IIIB–IVM1c melanoma finds talimogene laherparepvec upregulates immune-cell populations in non-injected lesions

March 30, 2021

Huyabio International announces Phase 3 global clinical trial collaboration with Bristol Myers Squibb for subjects with unresectable or metastatic melanoma not previously treated with anti-PD-1 therapy

March 30, 2021

LATTICE radiotherapy plus immunotherapy shows promise in treating advanced bulky tumors

March 29, 2021

FDA issues a complete response letter (CRL) to Merck’s Keytruda for triple-negative breast cancer

March 26, 2021

Phase 2b VITAL study of gemogenovatucel-T immunotherapy demonstrates clinical benefit in homologous recombination proficient ovarian cancer

March 25, 2021

Bristol Myers Squibb announces RELATIVITY-047, a trial evaluating Anti-LAG-3 antibody relatlimab and Opdivo (nivolumab) in patients with previously untreated metastatic or unresectable melanoma

March 25, 2021

Immuno-oncology treatments finding success with Combination Therapies

March 25, 2021

Chronic immune-related adverse events appeared more common than previously thought after adjuvant anti-PD-1 immunotherapy for stage III to stage IV melanoma according to study published in JAMA Oncology

March 24, 2021

Keytruda plus chemotherapy gains US approval for advanced oesophageal cancer

March 24, 2021

Adjuvant nivolumab improves disease-free survival in resected esophageal/gastroesophageal junction cancer according to phase III CheckMate 577 trial

March 22, 2021

Eucure Biopharma announces that its anti-CTLA-4 antibody (YH001) in combination with Junshi Biosciences’ TUOYI has demonstrated encouraging anti-tumor activity in Phase I trial

March 19, 2021

Noxopharm commences IONIC immune-oncology trial to test Veyonda and Opdivo combination against a range of tumor types

March 19, 2021

Merck and Eisai’s Keytruda-Lenvima Combo significantly improved progression-free survival in advanced endometrial cancer.

March 19, 2021

Phase II trial announced for regorafenib in combination with nivolumab in patients with refractory or recurrent osteosarcoma

March 18, 2021

Tilsotolimod plus Yervoy combo fails in anti-PD-1 refractory melanoma study

March 14, 2021

FDA evaluates status of 6 cancer drug indications that were granted accelerated approvals

March 12, 2021

AVEO Oncology announces collaboration with Bristol Myers Squibb to evaluate tivozanib and nivolumab combination for advanced relapsed or refractory renal cell carcinoma

March 11, 2021

Nouscom receives approval to begin phase 1b trials for novel personalized cancer immunotherapy

March 8, 2021

Roche withdraws Tecentriq for use treating people with bladder cancer whose disease has progressed after chemotherapy

March 5, 2021

Study observes survival improvement with Opdivo plus chemotherapy for the treatment of gastric and GEJ cancers

March 2, 2021

Researchers at Moffitt Cancer Center suggests that sequential administration of immunotherapy followed by targeted therapy prolongs anti-tumor responses in preclinical models

March 2, 2021

Merck & Co. voluntarily withdraws Keytruda’s indication in third-line small cell lung cancer

March 2, 2021

Phase III CONFIRM trial suggests effective use of Opdivo after chemotherapy for malignant pleural mesothelioma

March 2, 2021

Opdivo-Yervoy combination plus two cycles of platinum doublet chemotherapy shows significant improvement in survival of patients with advanced non-small cell lung cancer

March 1, 2021

Researchers at Columbia and MIT created a new technique called Perturb-CITE-sequencing to identify previously unknown resistance mechanisms to immune checkpoint inhibitors in melanoma patients

March 1, 2021

Researchers target p53 and RAS proteins in cancer immunotherapy using bispecific antibodies to curb tumor growth

February 26, 2021

The Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has recommended approval of Opdivo in combination with Cabometyx for the first-line treatment of adults with renal cell carcinoma to be reviewed by the European Commission (EC)

February 25, 2021

Compugen reports encouraging results from their phase I study of COM701 monotherapy and in combination with Opdivo for various types of cancers

February 23, 2021

NeoImmuneTech receives U.S. FDA Investigational New Drug Clearance for Pilot Study of NT-17 (efineptakin alfa) for Progressive Multifocal Leukoencephalopathy

February 22, 2021

Cemiplimab approved as front-line therapy for advanced NSCLC

February 22, 2021

FDA grants Fast Track Designation to GEN-1 immunotherapy for patients with advanced stage III or IV ovarian cancer

February 22, 2021

AstraZeneca to withdraw Imfinzi in advanced bladder cancer treatment in the U.S. after confirmatory trial showed no improvement of Imfinzi checkpoint inhibitor use over chemotherapy

February 20, 2021

Australian researchers identify protein linked to better patient responses to checkpoint inhibitor immunotherapy

February 19, 2021

Immunocore’s novel bispecific protein, tebentafusp, granted Breakthrough Therapy Designation, Fast Track Designation, and Orphan Drug Designation from the FDA for uveal melanoma

February 18, 2021

New trial funding for Nektar Therapeutics’ bempegaldesleukin drug paired with Merck’s pembrolizumab for squamous cell carcinoma of the head and neck

February 18, 2021

Study findings by researchers at Memorial Sloan Kettering Cancer Center suggest that blocking cancer cells’ use of sugar could increase the effectiveness of immunotherapy

February 18, 2021

Phase III OlympiA trial investigating effect of PARP inhibitor Lynparza shows positive results in adjuvant setting for patients with early breast cancer

February 17, 2021

Immunitas Therapeutics uses single-cell RNA-sequencing to identify the NK gene KLRB1 as a candidate inhibitory receptor on NK and T cells with applicability as a target in cancer immunotherapy

February 17, 2021

Research suggests that cosmetic lasers may make immune checkpoint inhibitors more effective in treating cancers with low mutation numbers

February 17, 2021

Phase 2 of neoadjuvant tavokinogene teleplasmid plus nivolumab study doses first patient with operable, locally or regionally advanced melanoma before surgery

February 16, 2021

Immunotherapy-docetaxel combinations show promise in metastatic castration-resistant prostate cancer

February 16, 2021

Study findings indicate promising use of cord blood-derived natural killer immunotherapy in combination with high-dose chemotherapy and autologous stem cell transplant in patients with B-cell non-Hodgkin lymphoma

February 15, 2021

Ludwig Cancer Research study identified novel mechanism for cancer immunotherapy using cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) blockade to disable suppressive immune cells

February 15, 2021

Study from the University of Pittsburgh School of Medicine suggests MCT1 inhibition drugs may boost effects of cancer immunotherapy

February 15, 2021

FDA approves nivolumab-cabozantinib as first-line treatment of advanced renal cell carcinoma

February 11, 2021

Repertoire Immune Medicines and Dana-Farber Cancer Institute announce new research collaboration aimed to identify novel tumor antigen targets relevant to HPV+ head and neck tumors

February 10, 2021

Nivolumab plus ipilimumab increases overall survival in patients with malignant pleural mesothelioma

February 10, 2021

FDA ODAC votes against recommending Keytruda for breast cancer

February 10, 2021

Case study analyzes successful Nivolumab treatment for head and neck squamous cell carcinoma after allogeneic bone marrow transplantation

February 10, 2021

FDA approves the chimeric antigen receptor (CAR) T-cell therapy Breyanzi, lisocabtagene maraleucel, for large B-cell lymphomas

February 10, 2021

Targovax and Papyrus will run pre-clinical research to evaluate the feasibility of combining Oncolytic Virus (ONCOS) and Opioid Binding Protein/Cell Adhesion Molecule-like (OPCML) tumor suppressor technology

February 10, 2021

Smectite promotes probiotic biofilm formation in gut for cancer immunotherapy

February 10, 2021

Study links greater survival benefits from immunotherapy in Black men to increased tumor plasma cells

February 8, 2021

Bristol Myers Squibb’s Opdivo reduces recurrence of muscle-invasive urothelial carcinoma

February 8, 2021

4D pharma announces new clinical trial using combined MRx0518, a Live Biotherapeutic product, and BAVENCIO monotherapies for locally advanced or metastatic urothelial carcinoma

February 8, 2021

Combination of Keytruda and Yervoy fails to prolong survival and delay disease progression of advanced non-small cell lung cancer

February 8, 2021

Joint radionuclide and immunotherapy approach for prostate cancer effective in mice

February 8, 2021

Multigene variant profiling assay to guide targeted immunotherapy selection in solid tumors

January 25, 2021

Korea-based microbiome technology company, Genome & Company, utilizes microbiome-based drugs in combination with Merck and Pfizer’s Bavencio in new U.S. clinical trials

January 13, 2021

FDA Grants Fast Track Designations in Merkel Cell Carcinoma, Cutaneous Squamous Cell Carcinoma

January 13, 2021

Istari wins orphan drug designation for melanoma therapy

January 11, 2021

Age May Not Impact Outcomes from Metastatic Renal Cell Carcinoma Treatment Despite Increased Toxicity in Older Patients

January 9, 2021

A Drug Indication Is Pulled From the Market: Now What?

January 8, 2021

Cavrotolimod Plus PD-1 Blockers Showing Efficacy in Advanced Cancers, Trial Reports

January 8, 2021

OncoSec Announces First Patient Dosed in Phase 2 Trial of TAVO™ Plus OPDIVO® as Neoadjuvant Therapy for Melanoma

January 7, 2021

Eganelisib/Nivolumab Shows Encouraging Efficacy in Advanced, Metastatic Urothelial Carcinoma

January 4, 2021

Triple Combo With Libtayo Shows Promise in Hard-to-treat Brain Cancer

January 2, 2021

Sabatolimab Demonstrates Promising Efficacy in Acute Myeloid Leukemia, Myelodysplastic Syndrome

December 23, 2020

The Society for Immunotherapy of Cancer (SITC) recommends actions for patients concerning SARS-CoV-2 vaccination and cancer immunotherapy

December 10, 2020

Results from First Combination Trial of ENHERTU® and Immune Checkpoint Inhibitor in Patients with HER2 Expressing Metastatic Breast Cancer Presented at the 2020 San Antonio Breast Cancer Symposium

December 9, 2020

Stellar Results from Kintor’s GT90001 and Opdivo Combo Therapy in the Second-line Treatment of Advanced Liver Cancer

December 7, 2020

Researchers identify potential drug combination to treat uveal melanoma

December 7, 2020

FDA Approves Less Frequent Treatment Regimen for Imfinzi in NSCLC, Bladder Cancer

December 7, 2020

Activity of Brentuximab Vedotin Plus Nivolumab Clinically Meaningful for Subset of Patients with HL

December 6, 2020

Personalized cancer vaccine shows promise in combination with pembrolizumab in HNSCC (presented at SITC)

December 4, 2020

Nivolumab demonstrates survival benefits in the adjuvant setting (indirect treatment comparison study presented at SITC)

December 3, 2020

Neoadjuvant Nivolumab Safe for Nonmetastatic High-Risk RCC

December 2, 2020

An Illustrative Case of Combination Cabozantinib/Nivolumab for Progressive Metastatic Renal Cell Carcinoma (mRCC).

December 2, 2020

ONCOS-102 plus pembrolizumab induces responses in anti-PD1-refractory melanoma

November 30, 2020

Nivolumab plus ipilimumab versus sunitinib for first-line treatment of advanced renal cell carcinoma: extended 4-year follow-up of the phase III CheckMate 214 trial.

November 13, 2020

Bempegaldesleukin plus nivolumab showed durable benefit in metastatic melanoma (SITC 2020)

November 13, 2020

Pembrolizumab approved in triple-negative breast cancer (TNBC)

November 8, 2020

Phase 2 Study Finds Nivolumab-Ipilimumab Combo Shows Activity in Metastatic Uveal Melanoma

November 7, 2020

TMB Use as Immunotherapy Biomarker Fraught by Challenges, But Still Shows Potential

November 6, 2020

Bristol Myers Squibb Receives European Commission Approval for Opdivo (nivolumab) plus Yervoy (ipilimumab) with Two Cycles of Chemotherapy for First-Line Treatment of Metastatic Non-Small Cell Lung Cancer

November 6, 2020

NICE rules nivolumab is not cost effective for use on NHS

November 3, 2020

Studies Find Connection Between Age and Melanoma Treatment Resistance

November 2, 2020

Libtayo Given FDA Priority Review for Advanced NSCLC With High PD-L1 Levels

October 31, 2020

Cabozantinib Plus Nivolumab Improves Efficacy Over Sunitinib in mRCC

October 19, 2020

How Do Melanoma Comorbidities Affect Patient Treatment Preferences?

September 21, 2020

ESMO 2020 Virtual Conference: Immunomedics wows ESMO with breast cancer data reveal

September 21, 2020

ESMO 2020 Virtual Conference: Late-breaking ESMO Presentation Shows Libtayo® (cemiplimab) Monotherapy Increases Overall Survival in First-line Advanced Non-small Cell Lung Cancer with PD-L1 Expression of ≥50%

September 21, 2020

ESMO 2020 Virtual Conference: QUANTITATIVE SUMMARY OF QOL DATA CONFIRMS IMMUNE CHECKPOINT INHIBITOR THERAPY IS GENERALLY WELL-TOLERATED

September 21, 2020

ESMO Virtual Conference 2020: IMMUNOTHERAPY IS BENEFICIAL IN GASTRIC AND ESOPHAGEAL CANCERS, STUDIES SHOW

September 20, 2020

ESMO 2020 Virtual Conference: PEMBROLIZUMAB DELIVERS CLINICAL BENEFIT IN SELECTED HISTOTYPES OF RARE SARCOMA

September 19, 2020

ESMO 2020 Virtual Conference: Results for Sacituzumab govitecan-hziy in breast and bladder support this antibody-drug conjugate

September 19, 2020

ESMO Virtual Conference 2020: Results from IO Therapy for Triple Negative Breast Cancer

September 19, 2020

ESMO Virtual Conference 2020: Nivolumab and cabozantinib effective in first-line treatment for metastatic kidney cancer

September 18, 2020

Durvalumab demonstrated unprecedented survival in unresectable, Stage III non-small cell lung cancer with an estimated 50% of patients surviving four years

September 18, 2020

2020 ESMO Virtual Congress 2020: Positive pivotal data for Libtayo® (cemiplimab) monotherapy in locally advanced basal cell carcinoma featured as a late-breaking presentation at ESMO

September 17, 2020

ESMO Virtual Congress 2020: Nivolumab + Ipilimumab vs. Sunitinib for First-Line Treatment of Advanced Renal Cell Carcinoma in CheckMate 214: 4-Year Follow-up and Subgroup Analysis of Patients without Nephrectomy

September 14, 2020

Adjuvant Opdivo shows promise in Esophageal-GEJ Cancer Patients

September 12, 2020

Higher Microbial Diversity May Be Associated with Better Outcomes in Patients with RCC

September 10, 2020

Validation of AI tools for cancer immunotherapy may be a step closer

September 10, 2020

Nivolumab/ipilimumab dual immune-checkpoint blockade active in mCRPC

September 8, 2020

Nivolumab/Ipilimumab Established as New Standard in Frontline sRCC

August 20, 2020

Merck’s oral cancer drug targeting STING boosts PD-1 immune blockade in mice

August 20, 2020

Immunotherapy Combo Shows Positive Results for Mesothelioma

August 19, 2020

Young Female Patients Have Low Response Rates to Immunotherapy

August 19, 2020

Pembrolizumab regimen extends survival in advanced esophageal cancer

August 19, 2020

Greater Diversity in Gut Microbiome Associated with Better Cancer Immunotherapy Outcomes

August 18, 2020

New App Helps Clinicians Manage Checkpoint Inhibitor AEs

August 15, 2020

CAR-NK Cell Immunotherapy Shows Promise

July 30, 2020

FDA Approves Atezolizumab Targeted Therapy Triple Combo for BRAF V600 Unresectable or Metastatic Melanoma

June 29, 2020

Cancer Vaccine Combo to be Tested in Triple Negative Breast Cancer

June 29, 2020

FDA Approves First-Line Immunotherapy for Patients with MSI-H/dMMR Metastatic Colorectal Cancer

June 27, 2020

Fecal Microbiota Transplant May Emerge as a Treatment Strategy in Melanoma Following Immunotherapy Failure

June 25, 2020

Noadjuvant Melanoma Combo Improves RFS in Macroscopic Melanoma

June 24, 2020

FDA Approves Pembrolizumab for Cutaneous Squamous Cell Carcinoma

June 9, 2020

Dramatic Drop in Skin Cancer Referrals During COVID-19 Crisis

June 8, 2020

New findings with immunotherapy in the adjuvant setting for Merkel Cell Carcinoma

June 8, 2020

Microbiotica, Cancer Research UK and Cambridge University Hospitals Collaborate in Landmark Cancer Microbiome Study

June 8, 2020

Personalized treatment strategies in melanoma could reduce toxicity burden from immunotherapy without compromising benefits

June 3, 2020

Replimune Provides RP1 Data Update from its Phase 2 Cohorts in Melanoma and Non-Melanoma Skin Cancer that Strongly Support Replimune’s Ongoing Registration-Directed Clinical Trials with RP1

May 28, 2020

Immunotherapy Avelumab Shows Potential in Rare Gynecologic Cancer Resistant to Chemotherapy

May 28, 2020

Pembrolizumab Doubles Time to Disease Progression in Patients With Advanced Colorectal Cancer With Specific DNA Mutations

May 18, 2020

FDA Approves Atezolizumab as a First-Line Treatment for Metastatic NSCLC Subgroup

April 28, 2020

FDA Approves Every-6-Week Pembrolizumab Dosage

April 27, 2020

Data Demonstrate Efficacy and Safety of KEYTRUDA 400 mg Every Six Weeks (Q6W) Comparable to Approved 200 mg Every Three Weeks (Q3W) Regimen

April 27, 2020

Atezolizumab Plus Vemurafenib/Cobimetinib Impresses in BRAF V600+ Melanoma

April 10, 2020

Checkpoint Combo Runs the Table in Early CRC

March 31, 2020

Skin Cancer Education & Research Foundation Launches New Website – A New Resource for the Fight Against Skin Caner.

March 25, 2020

Seattle Cancer Care Alliance, at the epicenter of the US epidemic, provides insights for cancer care during the evolving the COVID-19 crisis.

February 12, 2020

Merck’s KEYTRUDA® (pembrolizumab) in Combination with Chemotherapy Met Primary Endpoint of Progression-Free Survival (PFS) as First-Line Treatment for Metastatic Triple-Negative Breast Cancer (mTNBC)

February 12, 2020

Dealing with Coronavirus (COVID-19): Recommendations from the CDC

February 11, 2020

Seattle Genetics, Astellas, and Merck Hit a Bladder Cancer Bullseye

February 11, 2020

Jounce Using New Predictive Biomarker to Select Patients for Upcoming Phase II Immunotherapy Trial

February 10, 2020

Geneos to Test GNOS-PV02 Cancer Vaccine in Triple Combo Trial for Advanced Liver Cancer

February 3, 2020

First Patient Dosed in Proof-of-concept Study of CS1001 Plus Stivarga for Advanced Solid Tumors

January 26, 2020

Genentech Submits Supplemental Biologics License Application to the FDA for Tecentriq in Combination With Avastin for the Most Common Form of Liver Cancer

January 23, 2020

FDA to Review Tecentriq-Avastin Combo for Newly Diagnosed Advanced Liver Cancers

January 15, 2020

U.S. Food and Drug Administration Accepts for Priority Review Bristol-Myers Squibb’s Application for Opdivo (nivolumab) Plus Yervoy (ipilimumab) in First-Line Non-Small Cell Lung Cancer

January 13, 2020

Influenza Vaccines Triggers Immune System Response in Tumors

January 12, 2020

Positive Final 2-Year Topline Data in Completed DC Vaccine Phase I/II trial in AML Patients

January 11, 2020

Early-Stage Leukemia Vaccine Study Reports 80% Survival Rate

January 8, 2020

FDA approves Keytruda for BCG-unresponsive, high-risk non-muscle invasive bladder cancer

January 8, 2020

U.S. cancer death rate sees largest yearly drop

January 3, 2020

Tislelizumab-Chemo Combo Induces Durable Responses in Patients with Stomach, Esophagus Cancers, Trial Data Show

December 13, 2019

Genentech Announces Phase III Study Results for Tecentriq Plus Cotellic and Zelboraf in People With Previously Untreated BRAF V600 Mutation-positive Advanced Melanoma

December 9, 2019

ASH 2019: Brentuximab Vedotin in Combination with Nivolumab in Frontline and R/R Hodgkin Lymphoma

December 9, 2019

Nivolumab shows promise in ‘wide variety’ of mismatch repair-deficient cancers

December 8, 2019

Experimental immunotherapy can put patients with relapsed or refractory lymphoma into remission

December 8, 2019

ALX Oncology Presents Initial Data from the ALX148 Clinical Trial Non-Hodgkin Lymphoma Combination Cohort at the 61st American Society of Hematology (ASH)

December 8, 2019

Hyperprogression Halts Study of Nivolumab in Peripheral T-Cell Lymphomas

December 8, 2019

Speeding Access To New And Innovative Cancer Treatments

November 20, 2019

Opdivo/Yervoy combo for melanoma fails in key patient population

November 1, 2019

5-year survival data positive for nivolumab-based regimens in advanced melanoma

November 1, 2019

STING pathway may be key to tumor cell recognition by immune cells

October 29, 2019

ASDS Steering committee develops evidence-based consensus on cSCC staging, workup, treatment

October 28, 2019

Managing Hematological Immune-Related Adverse Events With Immune Checkpoint Inhibitors

October 28, 2019

Nivolumab improves survival in non-small cell lung carcinoma, study results suggest

October 28, 2019

IMFINZI® (durvalumab) and IMFINZI Plus Tremelimumab Delayed Disease Progression in Phase III POSEIDON Trial for 1st-Line Treatment of Stage IV Non-Small Cell Lung Cancer

October 28, 2019

Keytruda Survival Benefits Similar to Chemo for Relapsed Mesothelioma, Phase 3 Trial Finds

September 27, 2019

Maeton’s OT101 Gets Rare Pediatric Disease Designation for Childhood Brain Tumor

September 27, 2019

Systemic immune response in squamous cell carcinoma of the head and neck: A comparative concordance index analysis

September 26, 2019

Tasmanian devil research could help tackle immunotherapy resistance

September 26, 2019

Cognitive Impairment Following Immunotherapy Treatment May Be Underestimated

September 26, 2019

IL-10-based therapy shows promise when used in combination with anti-PD1 agents in lung and RCC

September 26, 2019

Metabolic Imbalance Associated with Resistance to Checkpoint Inhibitor Nivolumab

September 26, 2019

Boost in Survival Rates for Younger Patients With Melanoma Attributed to Immunotherapy Agents

September 4, 2019

Nivolumab more effective versus investigator’s choice in younger vs older patients with recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141)

September 4, 2019

TGF-Beta may be a predictive biomarker for response to pembrolizumab in HCC

September 3, 2019

Pooled Analysis Shows Triple OS with Nivolumab in Advanced NSCLC

August 30, 2019

Myasthenia gravis induced by avelumab

August 22, 2019

Anti-TNF therapy given concurrently with ICI therapy may be beneficial in patients with GI irAEs

August 16, 2019

Nivolumab plus ipilimumab versus sunitinib in first-line treatment for advanced renal cell carcinoma: extended follow-up of efficacy and safety results from a randomized, controlled, phase 3 trial

August 16, 2019

Serum Lactate Dehydrogenase Before Nivolumab Treatment Could Be a Therapeutic Prognostic Biomarker for Patients With Metastatic Clear Cell Renal Cell Carcinoma

August 16, 2019

ADXS-NEO Provoked Strong Immune Response in Advanced Cancer Patient, Early Trial Data Show

August 14, 2019

ICIs may trigger rare form of bullous pemphigoid

July 27, 2019

Wealth of Immunotherapy Combinations Places Emphasis on Biomarkers for NSCLC

July 26, 2019

PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma

July 25, 2019

Update on Frontline Nivolumab/Ipilimumab Combo Demonstrates Positive OS Results in PD-L1+ NSCLC

July 19, 2019

Prophylactic anti-TNF Therapy Improves Safety of Immunotherapies, Mouse Study Says

July 12, 2019

Libtayo Approved in Europe to Treat Metastatic or Advanced Cutaneous Squamous Cell Carcinoma

July 10, 2019

Trial Will Test Thermal Ablation, Followed By IP-001 Immunotherapy, Against Solid Tumors

June 19, 2019

Implementation of a Multidisciplinary Approach for Managing Immunotherapy-Related Toxicities

June 18, 2019

Colorectal Cancer Vaccine Candidate Induces Potent Immune Responses, Interim Trial Results Show

June 18, 2019

Phase 1 Study Demonstrates Safety of Pembrolizumab in Patients With HIV and Advanced Cancer

June 18, 2019

Keytruda approved for metastatic small cell lung cancer that has progressed after previous treatment

June 4, 2019

Alternate Doses of Ipilimumab Show Similar Results in Advanced Melanoma

May 27, 2019

Last Patient Enrolled in the Phase 2 Trial with Transgene’s TG4010 + Nivolumab + Chemotherapy for the First-Line Treatment of Advanced Lung Cancer (NSCLC)

May 22, 2019

Neurologic toxicity associated with immune checkpoint inhibitors: a pharmacovigilance study

May 17, 2019

Nivolumab with ipilimumab: Combination has added benefit in advanced renal cell carcinoma

May 16, 2019

First-Line Therapy for Metastatic RCC Remains Controversial Amid New Approvals

May 16, 2019

Immunotherapy response differs by EFGR mutation subtype

May 16, 2019

FDA approves Bavencio with Inlyta for patients with advanced renal cell carcinoma

May 14, 2019

Adopted cell transfer therapy being studied in sarcoma

May 2, 2019

Anti-BCMA CAR T-Cell Therapy bb2121 in Relapsed or Refractory Multiple Myeloma.

May 1, 2019

Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy

April 30, 2019

Keytruda-Inlyta combo approved by FDA for untreated advanced kidney cancer

April 22, 2019

FDA Approves Merck’s KEYTRUDA® (pembrolizumab) in Combination With Inlyta® (axitinib) as First-Line Treatment for Patients With Advanced Renal Cell Carcinoma (RCC)

April 16, 2019

Clinical Trial in Ireland Investigates Cellular Immunotherapy as Treatment for Two Autoimmune Liver Diseases

April 15, 2019

The Gut Microbiome & Cancer Immunotherapy

April 15, 2019

Recent Clinical Trials Explore Immunotherapies for Urothelial Carcinoma

April 15, 2019

Cancers ‘change spots’ to avoid immunotherapy

April 12, 2019

TKI-Immunotherapy Combinations Push the Envelope in Frontline RCC

April 11, 2019

First Off-the-Shelf Immunotherapy Clinical Trial Launched

April 11, 2019

FDA Expands Keytruda Indication for First-Line Treatment of Non-Small Cell Lung Cancer

April 10, 2019

Comorbidities Result in Fewer Patients in Clinical Trials

April 10, 2019

Researchers Develop Treatment That Turns Tumors Into Cancer Vaccine Factories

April 10, 2019

AZ and MSD’s Lynparza gets EU nod for hard-to-treat breast cancer

April 9, 2019

Incysus Therapeutics gets FDA approval for brain cancer treatment trial

April 9, 2019

SWOG cancer research network study opens window into immune microenviroment

April 9, 2019

The changing landscape of diagnostic biomarkers: Exploring the one-biomarker-per-drug paradigm in oncology

April 8, 2019

Cancer ‘vaccine’ shows promise in human trial of lymphoma patients

April 8, 2019

Clinical Trial Investigates Orbsen Therapeutics’ ORBCEL-C™ Immunotherapy as Treatment for Two Autoimmune Liver Diseases

April 7, 2019

Researchers Develop “Swiss Army Knife” Immunotherapy to “Kick and Kill” HIV

April 5, 2019

Fecal transplants could help patients on cancer immunotherapy drugs

April 2, 2019

Gut microbes can spur immune system to attack cancer

April 1, 2019

UC San Diego Health Treats 1st Cancer Patient with Stem-Cell Derived Natural Killer Cells

April 1, 2019

Despite research boom, few immunotherapy studies targeting pancreatic cancer

April 1, 2019

How immune cells help tumors escape body’s defenses

March 31, 2019

AACR 2019 Research Roundup: Pancreatic Cancer Immunotherapy, Prostate Cancer Drug Resistance, Insight into Inherited Cancer Mutations

March 30, 2019

ETH researchers take major step towards personalized cancer immunotherapy

March 29, 2019

Combining DNA Damage Response Inhibitors with Immunotherapy Boosts SCLC Clearance, Mouse Study Shows

March 29, 2019

Immunotherapy for Pre-Cancerous Lesions May Reduce Skin Cancer Risk Over Time

March 28, 2019

Harnessing T-cell “stemness” could enhance cancer immunotherapy

March 28, 2019

Better Muscle Mass Linked to Improved Immunotherapy Response

March 28, 2019

New study confirms EpCAM as promising target for cancer immunotherapy

March 24, 2019

Bladder Cancer Guidelines Showcase Advent of Immunotherapy

March 22, 2019

FDA Approves Tecentriq/Chemo for Newly Diagnosed Extensive-stage SCLC

March 21, 2019

Immunotherapies for Staphylococcus aureus

March 21, 2019

Imugene gains guidance for KEY-Vaxx Immunotherapy development

March 21, 2019

New U.K. Partnership Aims To Improve Access Immunotherapy For Cancer Patients

March 21, 2019

OHSU Knight Cancer Institute Throws Out Old System Of Clinical Trials

March 20, 2019

EU Approves Keytruda/Chemo Combo to Treat Metastatic Squamous NSCLC

March 18, 2019

Cytovation Initiates Clinical Development Programme With CyPep-1, a First-in-class Lytic Agent for Tumor Immunotherapy

March 15, 2019

TC BioPharm, Trinity College Dublin Pair to Develop Cancer-fighting Cell Therapy

March 13, 2019

Current Treatment of Esophageal Cancer and Promising Clinical Trials Underway

March 13, 2019

Immune Checkpoint Inhibitors Safe, Effective in HIV-positive Patients with Advanced Cancer, Research Reveals

March 12, 2019

Harness the immune system to fight colon cancer

March 11, 2019

FDA Approves Tecentriq-Abraxane Combo as First Immunotherapy Regimen for Breast Cancer

March 11, 2019

Unique Immunotherapy Combinations Provide an Optimistic Outlook in Early Urothelial Carcinoma Trials

March 8, 2019

Precision drugs could unmask cancers to immune system and boost effects of immunotherapy

March 8, 2019

FDA approves 1st immunotherapy drug to treat breast cancer

March 8, 2019

Immunotherapy in Bladder Cancer

March 8, 2019

More News! Targeting tuberculosis, light-activated drugs, cancer immunotherapies and more

March 8, 2019

Recognizing Endometrial Tumor Immune Features Is Key to Treatment Success